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Peter Igarashi Selected Research

Cystic Kidney Diseases (Cystic Kidney Disease)

1/2020Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression.
11/2019Hepatocyte nuclear factor-1β regulates Wnt signaling through genome-wide competition with β-catenin/lymphoid enhancer binding factor.
1/2018Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling.
10/2015Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNA.
6/2011Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.
6/2008Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.

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Peter Igarashi Research Topics

Disease

19Cysts
01/2020 - 10/2002
11Polycystic Kidney Diseases (Polycystic Kidney Disease)
01/2020 - 04/2003
6Cystic Kidney Diseases (Cystic Kidney Disease)
01/2020 - 06/2008
5Autosomal Dominant Polycystic Kidney (ADPKD)
01/2020 - 06/2008
4Kidney Diseases (Kidney Disease)
01/2021 - 11/2017
4Fibrosis (Cirrhosis)
01/2020 - 09/2010
4Inflammation (Inflammations)
01/2020 - 03/2013
3Acute Kidney Injury (Acute Renal Failure)
12/2019 - 05/2003
3Renal cysts and diabetes syndrome
12/2007 - 03/2004
2Proteinuria
01/2018 - 03/2013
2Body Weight (Weight, Body)
04/2008 - 01/2008
2Carcinogenesis
01/2008 - 02/2005
2Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I)
11/2005 - 03/2005
1Chronic Kidney Failure (Chronic Renal Failure)
01/2020
1Sepsis (Septicemia)
12/2019
1Hypokalemia
11/2017
1Disease Progression
06/2013
1Lupus Nephritis
03/2013
1Ischemia
09/2012
1Prune Belly Syndrome
01/2012
1Acidosis
06/2009
1Splenomegaly
04/2009
1Birt-Hogg-Dube Syndrome
01/2008
1Diabetes Mellitus
12/2007
1Polyneuropathies (Polyneuropathy)
09/2007
1Amyloidosis
09/2007
1Leiomyomatosis
04/2007
1Renal Cell Carcinoma (Grawitz Tumor)
04/2007
1Renal Insufficiency (Renal Failure)
11/2005
1Reperfusion Injury
07/2005
1Hypersensitivity (Allergy)
03/2004
1Atrophy
02/2004

Drug/Important Bio-Agent (IBA)

8Hepatocyte Nuclear Factor 1-betaIBA
01/2010 - 10/2002
4MicroRNAs (MicroRNA)IBA
01/2020 - 12/2012
4Transcription Factors (Transcription Factor)IBA
01/2020 - 01/2010
3CateninsIBA
11/2019 - 09/2012
3Proteins (Proteins, Gene)FDA Link
09/2013 - 11/2006
2Long Noncoding RNAIBA
01/2020 - 01/2018
2ChromatinIBA
01/2020 - 01/2009
2RNA (Ribonucleic Acid)IBA
10/2018 - 01/2018
2Urea (Carbamide)FDA LinkGeneric
01/2018 - 03/2013
2TamoxifenFDA LinkGeneric
01/2018 - 03/2013
2NitrogenIBA
01/2018 - 03/2013
2Pharmaceutical PreparationsIBA
01/2017 - 07/2010
2Sirolimus (Rapamycin)FDA Link
07/2010 - 01/2008
2beta CateninIBA
02/2005 - 04/2003
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
01/2020
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2020
1X-Box Binding Protein 1IBA
12/2019
1LipopolysaccharidesIBA
12/2019
1EndotoxinsIBA
01/2018
1Bovine Serum AlbuminIBA
01/2018
1Cyclic AMP (AMP, Cyclic)IBA
01/2018
1NucleotidesIBA
01/2018
1Adenylyl Cyclases (Adenylyl Cyclase)IBA
01/2018
1InflammasomesIBA
01/2018
1Potassium Channels (Potassium Channel)IBA
11/2017
1ElectrolytesIBA
11/2017
1TRPP Cation ChannelsIBA
09/2013
1CreatinineIBA
03/2013
1Kallikreins (Kallikrein)IBA
03/2013
1Ribonuclease III (RNase III)IBA
12/2012
1Folic Acid (Vitamin M)FDA LinkGeneric
09/2012
1DNA (Deoxyribonucleic Acid)IBA
01/2012
1A Kinase Anchor ProteinsIBA
06/2011
1Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
06/2011
1Transforming Growth Factor beta (TGF-beta)IBA
09/2010
1alpha2 Subunit Collagen Type IIBA
09/2010
1CollagenIBA
09/2010
1AmmoniaIBA
06/2009
1LipidsIBA
06/2009
1AcidsIBA
06/2009
1Glycoproteins (Glycoprotein)IBA
06/2009
1Peptides (Polypeptides)IBA
04/2009
1AutoantibodiesIBA
04/2009
1KinesinsIBA
01/2009
1triptolideIBA
09/2008
1Phosphotransferases (Kinase)IBA
06/2008
1U 0126 (UO 126)IBA
06/2008
1Cre recombinaseIBA
06/2008
1Glucose (Dextrose)FDA LinkGeneric
04/2008
1Saline SolutionIBA
04/2008
1BuffersIBA
01/2008
1Prealbumin (Transthyretin)IBA
09/2007
1Messenger RNA (mRNA)IBA
05/2007
1Fumarate Hydratase (Fumarase)IBA
04/2007
1Membrane Proteins (Integral Membrane Proteins)IBA
11/2006
1Bromodeoxyuridine (BrdU)IBA
07/2005
1VimentinIBA
07/2005
1Deoxyribonucleases (DNase)FDA Link
03/2004
1Inositol (Myoinositol)IBA
02/2004
1Aldehyde Reductase (Aldose Reductase)IBA
02/2004
1Betaine (C.B.B.)FDA Link
02/2004
1gamma-Aminobutyric Acid (GABA)IBA
02/2004
1ErbB Receptors (EGF Receptor)IBA
04/2003
1kinesin-IIIBA
04/2003
1Cadherins (E-Cadherin)IBA
10/2002

Therapy/Procedure

3Therapeutics
01/2020 - 05/2003
1Traction
01/2021
1Intraperitoneal Injections
01/2018